Wednesday, October 21, 2009

Adult Stem Cell Science Gives Hope to Spinal Cord Injury Victims

When you "do" science in ways that do not offend God, He will bless your efforts abundantly. It's just that simple. Look at the ongoing breakthroughs being achieved by scientists using adult stem cells while the millions of hours (and billions of dollars!) spent on experiments in which human embryos are killed is producing nothing but false hope and failure.

Here's one of the latest examples of the difference in approaches.

A new study by a Wayne State University School of Medicine researcher details the outcome of adult stem cell grafts in spinal cord injuries and how the procedure led to increased mobility and quality of life for patients.

Associate Professor Jean Peduzzi-Nelson (see photo) of the Department of Anatomy and Cell Biology conducted the study, “Olfactory Mucosal Autografts and Rehabilitation for Chronic Traumatic Spinal Cord Injury,” which was published online in the journal Neurorehabilitation and Neural Repair...


In the study, 20 patients with severe chronic spinal cord injuries received a treatment combination of partial scar removal, transplantation of nasal tissue containing stem cells to the site of the spinal cord injury and rehabilitation. All of the patients had total paralysis below the level of their spinal cord injury before the treatment.


“This may be the first clinical study of patients with severe, chronic spinal cord injury to report considerable functional improvement in some patients with a combination treatment,” Peduzzi-Nelson said. “Normally, in people with spinal cord injuries that happened more than 18 months ago, there is little improvement.”

The injuries in the study patients were 18 months to 15 years old. The patients, ages 19 to 37, had no use of their legs before the treatment. One paraplegic treated almost three years after the injury now ambulates with two crutches and knee braces. Ten other patients ambulate with physical assistance and walkers (with and without braces). One 31-year-old male tetriplegic patient uses a walker without the help of knee braces or physical assistance. When the stem cell transplant and scar removal process was combined with an advanced form of rehabilitative training that employs brain-initiated weight-bearing movement, 13 patients improved in the standard measures used to assess functional independence and walking capabilities...

The partial scar removal and tissue transplantation procedures were performed in Portugal. The rehabilitation of patients took place in Italy and Portugal...Peduzzi-Nelson said that she and Jay Meythaler, M.D., chairman of the Department of Physical Medicine and Rehabilitation, along with other colleagues, are seeking FDA approval to perform the procedure in the United States.